If a patient receiving clonidine is also taking neuroleptics, orthostatic regulation disturbances e. Monitor heart rate in patients receiving clonidine concomitantly with agents known to affect sinus node function or AV nodal conduction, e. Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concomitantly with diltiazem or verapamil.
Amitriptyline in combination with clonidine enhances the manifestation of corneal lesions in rats see Toxicology. Based on observations in patients in a state of alcoholic delirium it has been suggested that high intravenous doses of clonidine may increase the arrhythmogenic potential QTprolongation, ventricular fibrillation of high intravenous doses of haloperidol.
Causal relationship and relevance for clonidine oral tablets have not been established. Sudden cessation of clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and tremor accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma.
The likelihood of such reactions to discontinuation of clonidine therapy appears to be greater after administration of higher doses or continuation of concomitant beta-blocker treatment and special caution is therefore advised in these situations. Rare instances of hypertensive encephalopathy , cerebrovascular accidents and death have been reported after clonidine withdrawal.
An excessive rise in blood pressure following discontinuation of CATAPRES tablets therapy can be reversed by administration of oral clonidine hydrochloride or by intravenous phentolamine.
If therapy is to be discontinued in patients receiving a beta-blocker and clonidine concurrently, the beta-blocker should be withdrawn several days before the gradual discontinuation of CATAPRES tablets. Because children commonly have gastrointestinal illnesses that lead to vomiting, they may be particularly susceptible to hypertensive episodes resulting from abrupt inability to take medication. In patients who develop an allergic reaction to Catapres-TTS, substitution of oral clonidine hydrochloride may also elicit an allergic reaction including generalized rash, urticaria , or angioedema.
The sympatholytic action of clonidine may worsen sinus node dysfunction and atrioventricular AV block, especially in patients taking other sympatholytic drugs. Blood pressure should be carefully monitored during surgery and additional measures to control blood pressure should be available if required.
There was no evidence of genotoxicity in the Ames test for mutagenicity or mouse micronucleus test for clastogenicity. Increased resorptions were not associated with treatment at the same time or at higher dose levels up to 3 times the oral MRDHD when the dams were treated on gestation days 6 to No adequate, well-controlled studies have been conducted in pregnant women.
Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. The frequency of CNS depression may be higher in children than adults. Large overdoses may result in reversible cardiac conduction defects or dysrhythmias, apnea , coma and seizures. Signs and symptoms of overdose generally occur within 30 minutes to two hours after exposure.
As little as 0. There is no specific antidote for clonidine overdosage. Clonidine Catapress is a medication prescribed for the treatment of hypertension. Clonidine has also been prescribed to treat opiate withdrawal symptoms and attention deficit syndrome in children.
A search of the prescribing literature for clonidine lists dizziness as a common side effect and nausea and vomiting as less frequent side effects. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Consuelo Worley, RPh Q: Does clonidine cause weight gain? Drugs can cause weight gain in several different ways.
Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex. Some drugs have no effect on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals and weight loss in others. There are also drugs that initially cause weight loss and then lead to weight gain with long-term use.
Most prescription medications associated with changes in body weight affect the central nervous system. Mood stabilizers lithium, valproic acid , antipsychotics, and anticonvulsants have also been linked with weight gain.
Other drugs that have been reported to cause weight gain include diabetes medications insulin, sulfonylureas, and thiazolidinediones , antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors.
Catapres clonidine is a medication that is used in the treatment of high blood pressure. The most common side effects with clonidine are dry mouth, drowsiness, dizziness, constipation, sedation, low blood pressure, weakness, and nausea. A search of the prescribing information did not specifically list weight gain as a side effect. This is not a complete list of the side effects associated with clonidine. If you think a drug you are taking is causing weight gain, tell your health care provider.
Do not stop any medication or change the dose without first talking to your provider. Megan Uehara, PharmD Q: Dealing with diabetes and trying to get my numbers down, I took atenolol for 14 yrs at bedtime for blood pressure. Now instead I'm on clonidine. My numbers for blood sugar are high in the morning. My numbers are a little lower in the morning, about 50 pts lower. Does clonidine affect blood sugar levels?
I have reviewed your question regarding Tenormin atenolol , Catapres clonidine and your blood glucose levels. There have also been rare reports of severe, possibly fatal reactions such as stroke from stopping this drug too quickly. Therefore, it is important that you do not run out of clonidine or miss any doses. Tell your doctor or pharmacist right away if you are unable to take the medication for example, due to vomiting.
To prevent any reactions while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away. When used for a long time, this medication may not work as well and may require different dosing or an additional medication.
Agitation, anxiety, deliriumdelusional perception, hallucinations including visual and auditoryinsomnia, mental depression, nervousness, other behavioral changes, paresthesiaclonidine, sleep disorder, and vivid dreams or nightmares. Tolerance to the antihypertensive effect may develop in some patients, necessitating a reevaluation of therapy, clonidine. 3 mg. Normal postural reflexes are intact; therefore, orthostatic symptoms are mild and infrequent. Do not stop any medication or change the dose without clonidine talking to your provider. Leg cramps and muscle or joint pain. Your clonidine will write the number of refills authorized on your prescription, clonidine. 3 mg. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. Clonidine is a long-term medication. Signs and symptoms of overdose generally occur within 30 minutes to two hours after exposure. In view of the retinal degeneration seen in rats, eye examinations were performed during clinical trials in patients before, and periodically after, the start of clonidine therapy. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Sarah Lewis, clonidine. 3 mg, PharmD Q: Clonidine lowers blood pressure by decreasing the levels of certain chemicals clonidine your blood. The half-life increases up to 41 hours in patients with severe impairment of renal function. Uses Uses This medication is used alone or with other medications to treat high blood pressure hypertension. If you have a higher dose, take it at bedtime. Based on observations in clonidine in a state of alcoholic delirium it has been suggested that high intravenous doses of clonidine may increase the arrhythmogenic potential QTprolongation, ventricular fibrillation of high intravenous doses of haloperidol.
Normal postural reflexes are intact; therefore, orthostatic symptoms are mild and infrequent. General You can take clonidine with or without food. Toxicology In several studies with oral clonidine hydrochloride, clonidine. 3 mg, a dose-dependent increase in the incidence and severity of spontaneous retinal degeneration was seen in albino rats treated for six months or longer. There are other codeine stopped working available to treat your condition. Increased resorptions were not associated with treatment at the same time or at higher dose levels up to 3 times the oral MRDHD when the dams were treated on gestation days 6 to If a patient receiving clonidine is also taking neuroleptics, orthostatic regulation disturbances e. If a patient receiving clonidine hydrochloride is also taking tricyclic antidepressants, the hypotensive effect of clonidine may be reduced, necessitating an increase in the clonidine dose. Patients should be carefully monitored. Clonidine is used to treat hypertension high blood pressure. You may experience symptoms such as nervousness, agitation, shaking, and headache. The frequency of CNS depression may be higher in children than adults.
In patients who develop an allergic reaction to Catapres-TTS, substitution of oral clonidine hydrochloride may also elicit an allergic reaction including generalized rash, urticariaor clonidine. This is not a complete list of the side effects associated with clonidine. Renal Impairment Patients with renal impairment may benefit from a lower initial dose. My numbers for blood sugar are high in the morning. This information is not a substitute for medical advice. Monitor heart rate in patients receiving clonidine concomitantly with agents known to affect sinus node function or AV nodal conduction, e, clonidine. 3 mg. Always speak with your doctor or pharmacist about dosages that are right for you. Studies have indicated that 2. Cases of sinus bradycardia and atrioventricular block have been reported, both with and without the use of concomitant digitalis. Catapres clonidine is an alpha-blocker that is not used as often anymore, but can be an excellent choice in some cases. Drugs can cause weight gain in several different ways. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Elderly patients may benefit from a lower initial dose. Joseph Hall, RPh Q: Always carry it with you or in your carry-on bag. How to tell if the drug is working You may clonidine able to tell this drug is working if you notice improvement in your symptoms, especially attention, hyperactivity, clonidine. 3 mg, and impulsivity. Toxicology In several studies with oral clonidine hydrochloride, a dose-dependent increase in the clonidine and severity of spontaneous retinal degeneration was seen in albino rats treated for six months or longer, clonidine. 3 mg.
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