Tamoxifen is also used to lower a woman's chance of developing breast cancer if she has a high risk such as a family history of breast cancer. Tamoxifen may also be used for purposes not listed in this medication guide. Get emergency medical help if you have any of these signs of an allergic reaction: Stop using tamoxifen and call your doctor at once if you have a serious side effect such as: Less serious side effects may include: This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. What is the most important information I should know about tamoxifen Soltamox? Do not use tamoxifen if you are pregnant. It could harm the unborn baby.
Use a barrier form of birth control such as a condom or diaphragm with spermicide while you are using this medication and for at least 2 months after your treatment ends. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin Coumadin. Can tamoxifen cause high blood sugar?
According to the package insert, tamoxifen citrate Nolvadex does not have elevated blood sugar as a side effect that was reported during clinical trials or that has been reported after the drug was put to market. Post market research of tamoxifen Nolvadex does note a rare incidence of increased cholesterol and triglycerides, but not blood sugar. Please see the following Everyday Health link for more information on tamoxifen Nolvadex.
About three weeks ago I started having cramps in the backs of my legs. It only happens in the morning when I'm ready to get up. I've just started taking tamoxifen. Are the cramps one its possible side effects? Leg cramps are a common complaint among patients who take tamoxifen. It may help to make sure you stay hydrated throughout the day, and increase your intake of foods containing potassium.
You can also ask your physician if drinking tonic water would be an acceptable treatment, since tonic water contains small amounts of quinine, which may take the edge off your cramps. In any case, discuss this side effect with your physician. Matt Curley, PharmD Q: I have to make a decision on taking tamoxifen and I am concerned about the side effects of blood clots, vision and other cancers.
I am not sure the risks are worth the risks of changing the quality of my life if I suffer with side effects. My system is very sensitive to drugs in general. The results of therapy with any drug can be both positive and negative and it is always important to weight the potential benefits against the potential risks of treatment.
Depending on your diagnosis, and reason for taking tamoxifen, the benefits may be well proven. You should discuss these with your healthcare provider to have a full understanding of them and then evaluate them against the risks. According to the package insert, tamoxifen is generally well tolerated, with the most common side effects being hot flashes, vaginal dryness and a mild vaginal discharge. The risk of more serious side effects has been evaluated in scientific studies.
Over a period of nearly 7 years, the risk of uterine cancer in people taking tamoxifen is approximately 2 per 1, women-years. The risk of blood clots, including stroke and pulmonary embolism, is about For more information, please contact your healthcare provider.
Does tamoxifen cause fluid retention? As always, talk with your healthcare provider regarding possible side effects of your medication. Jen Marsico, RPh Q: I'm taking tamoxifen and have been given conflicting information. Do I need to avoid foods that contain phytoestrogens? Phytoestrogen foods are foods that are structurally similar to estrogen. Tamoxifen works by binding to estrogen receptors in the breast and other tissues to decrease the effects of estrogen. After performing an extensive search and review of clinical studies concerning phytoestrogens and tamoxifen, it is discovered that there is limited data and appears that additional studies need to be performed to fully understand if this combination is safe.
A journal article from referenced on the American Cancer Society's Web site states that there are animal studies indicating that a specific phytoestrogen could interfere with the effects of tamoxifen on breast cancer cells. Please talk with your health care provider, preferably your oncologist for additional information regarding eating phytoestrogen foods while taking tamoxifen. Jennyfer Marsico, RPh Q: I've experienced a racing heart and irregular heartbeat. Can tamoxifen cause these symptoms?
According to the package insert, common side effects of tamoxifen include bone pain, constipation, coughing, hot flashes, muscle pain, nausea, tiredness, vaginal discharge, and weight loss. A review of medical literature did not show reports of rapid heart rate or tachycardia or irregular heartbeat in patients taking tamoxifen. You are encouraged to report any negative side effects of prescription drugs to your health care practitioner and the Food and Drug Administration FDA by visiting www.
When my doctor put me on tamoxifen a year and a half ago, he told me not to eat soy products. I have ulcerative colitis and had been taking an over the counter pill Digestive Advantage for Colon Health that worked well.
A few months ago I noticed in the ingredient list that selenium soy was listed. I quit taking it but now my symptons have come back. Is there an over the counter product that does not contain soy? I was on Pentasa for several years 16 a day but found this product worked just as well. I don't want to go back on Pentasa if there is something else that will help. Soy has potential estrogen-like properties, so people receiving drugs like tamoxifen, which block the effects of estrogen, are often told to avoid soy products.
Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. Tamoxifen as adjuvant therapy in breast cancer. Dig Dis Sci ; Ann Intern Med ; Tamoxifen-associated steatohepatitis - report of three cases. J Hepatol ; Tamoxifen and secondary tumours. Drug Saf ; Tamoxifen in liver disease: Ann Oncol ; 9: Tamoxifen for prevention of breast cancer: J Natl Cancer Inst ; Tamoxifen-induced fatty liver in patients with breast cancer.
Cas Lek Cesk Aug 30; Cirrhosis with steatohepatitis after adjuvant tamoxifen. Bezafibrate for tamoxifen-induced non-alcoholic steatohepatitis. The association between tamoxifen and the development of hepatocellular carcinoma: Can J Surg ; Gastroenterol Clin Biol ; Toremifene-induced fatty liver and NASH in breast cancer patients with breast-conservation treatment.
Int J Oncol ; Tamoxifen-induced submassive hepatic necrosis. Cancer J ; 6: Unrecognized hepatic steatosis and non-alcoholic steatohepatitis in adjuvant tamoxifen for breast cancer patients. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose? Seek emergency medical attention or call the Poison Help line at What should I avoid while taking tamoxifen? This medicine can pass into body fluids urine, feces, vomit. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Tamoxifen side effects Get emergency medical help if you have signs of an allergic reaction to tamoxifen: Tamoxifen can increase your risk of stroke or blood clots. Call your doctor at once if you have: Also call your doctor at once if you have: Common tamoxifen ide effects may include:
A review of medical literature did not show reports use rapid heart rate or tachycardia or irregular heartbeat in patients taking tamoxifen. If you tamoxifen taking chemotherapy medications while taking tamoxifen, there is a small increase in the risk for developing blood clots. Benign hepatic cyst in a patient on how to get high with lortab therapy for metastatic breast cancer. When my doctor put me on tamoxifen a year and a half ago, he told me not to eat soy products. These breast cancers depend on estrogen to grow and tamoxifen works against the effects of estrogen on these cells, how to use tamoxifen 20 mg. A case of peliosis hepatis in association with tamoxifen therapy. Oncol Report ; The side effects are similar to those experienced during menopause. You may need to keep using this medication how up to 5 years. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant. I am not sure the risks are worth the risks of changing the quality of my life if I suffer with side effects. Certain types of breast cancer require estrogen to grow. Do I need to avoid foods that contain phytoestrogens? Fatty liver and drugs. You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. Tamoxifen works by binding to estrogen receptors in the breast and other tissues to decrease the effects of estrogen.
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