Carisoprodol can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Soma is not approved for use by anyone younger than 16 years old. Older adults may be more sensitive to the effects of this medicine. How should I take Soma? Take Soma exactly as it was prescribed for you. Follow all directions on your prescription label.
Do not take this medicine in larger or smaller amounts or for longer than recommended. Soma is usually taken 3 times per day and at bedtime. Follow your doctor's dosing instructions very carefully. This medicine should be used for only a short time; up to 2 or 3 weeks unless your doctor tells you otherwise. Never share Soma with another person, especially someone with a history of drug abuse or addiction.
Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Do not stop using carisoprodol suddenly after long-term use, or you could have unpleasant withdrawal symptoms.
Ask your doctor how to safely stop using this medicine. Soma is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.
Follow your doctor's instructions. Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Carisoprodol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Dosage Information in more detail What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose? Seek emergency medical attention or call the Poison Help line at An overdose of carisoprodol can be fatal, especially if you take this medicine with alcohol or with other drugs that can slow your breathing.
Carisoprodol is dialyzable by hemodialysis and peritoneal dialysis. Carisoprodol has been subject to abuse, misuse, and criminal diversion for nontherapeutic use [ see Warnings and Precautions 5.
Patients at high risk of SOMA abuse may include those with prolonged use of carisoprodol, with a history of drug abuse, or those who use SOMA in combination with other abused drugs. Prescription drug abuse is the intentional non-therapeutic use of a drug, even once, for its rewarding psychological effects. Drug addiction, which develops after repeated drug abuse, is characterized by a strong desire to take a drug despite harmful consequences, difficulty in controlling its use, giving a higher priority to drug use than to obligations, increased tolerance, and sometimes physical withdrawal.
Drug abuse and drug addiction are separate and distinct from physical dependence and tolerance for example, abuse or addiction may not be accompanied by tolerance or physical dependence [ see Drug Abuse and Dependence 9. Physical dependence is characterized by withdrawal symptoms after abrupt discontinuation or a significant dose reduction of a drug.
Both tolerance and physical dependence have been reported with the prolonged use of SOMA. Reported withdrawal symptoms with SOMA include insomnia, vomiting, abdominal cramps, headache, tremors, muscle twitching, anxiety, ataxia, hallucinations, and psychosis. Serotonin syndrome has been reported with carisoprodol intoxication.
Many of the carisoprodol overdoses have occurred in the setting of multiple drug overdoses including drugs of abuse, illegal drugs, and alcohol. The effects of an overdose of carisoprodol and other CNS depressants e. Basic life support measures should be instituted as dictated by the clinical presentation of the SOMA overdose. Vomiting should not be induced because of the risk of CNS and respiratory depression, and subsequent aspiration.
Circulatory support should be administered with volume infusion and vasopressor agents if needed. Seizures should be treated with intravenous benzodiazepines and the reoccurrence of seizures may be treated with phenobarbital. In cases of severe CNS depression, airway protective reflexes may be compromised and tracheal intubation should be considered for airway protection and respiratory support.
For decontamination in cases of severe toxicity, activated charcoal should be considered in a hospital setting in patients with large overdoses who present early and are not demonstrating CNS depression and can protect their airway.
Carisoprodol is a white, crystalline powder, having a mild, characteristic odor and a bitter taste. It is slightly soluble in water; freely soluble in alcohol, in chloroform, and in acetone; and its solubility is practically independent of pH.
Carisoprodol is present as a racemic mixture. Chemically, carisoprodol is N-isopropylmethylpropyl-1,3-propanediol dicarbamate and the molecular formula is C12H24N2O4, with a molecular weight of The structural formula is: Other ingredients in the SOMA drug product include alginic acid, magnesium stearate, potassium sorbate, starch, and tribasic calcium phosphate. In animal studies, muscle relaxation induced by carisoprodol is associated with altered interneuronal activity in the spinal cord and in the descending reticular formation of the brain.
A metabolite of carisoprodol, meprobamate, has anxiolytic and sedative properties.
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