You may report side effects to Health Canada at Quick GuideSymptoms of Mono: Before taking amoxicillin, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: Kidney function declines as you grow older.
This medication is removed by the kidneys. Therefore, elderly people may be more sensitive to this drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Amoxicillin passes into breast milk. Consult your doctor before breast-feeding. Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
Do not start, stop, or change the dosage of any medicine before checking with them first. Before taking amoxicillin, tell your doctor or pharmacist if you are also taking probenecid. AUGMENTIN was weakly positive in the mouse lymphoma assay, but the trend toward increased mutation frequencies in this assay occurred at doses that were also associated with decreased cell survival. Potassium clavulanate alone was tested in the Ames bacterial mutation assay and in the mouse micronucleus test, and was negative in each of these assays.
Based on body surface area, this dose of amoxicillin is approximately 4 times the maximum recommended adult human oral dose mg every 12 hours. For clavulanate, the dose multiple is approximately 9 times higher than the maximum recommended adult human oral dose mg every 8 hours , also based on body surface area. The amoxicillin doses in rats and mice based on body surface area were approximately 4 and 2 times the maximum recommended adult human oral dose mg every 12 hours. For clavulanate, these dose multiples were approximately 9 and 4 times the maximum recommended adult human oral dose mg every 8 hours.
There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Labor And Delivery Oral ampicillin class antibiotics are poorly absorbed during labor.
Nursing Mothers Amoxicillin has been shown to be excreted in human milk. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. This drug is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function.
Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. See Patients with Renal Impairment for specific recommendations in patients with renal impairment. Renal impairment appears to be reversible with cessation of drug administration.
Before initiating therapy with Augmentin, careful inquiry should be made regarding previous hypersensitivity reactions to penicillins, cephalosporins, or other allergens. If an allergic reaction occurs, Augmentin should be discontinued and appropriate therapy instituted.
Hepatic Dysfunction Hepatic dysfunction, including hepatitis and cholestatic jaundice has been associated with the use of Augmentin. Hepatic toxicity is usually reversible; however, deaths have been reported. Hepatic function should be monitored at regular intervals in patients with hepatic impairment. Clostridium difficile Associated Diarrhea CDAD Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Augmentin, and may range in severity from mild diarrhea to fatal colitis.
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin-producing strains of C. CDAD must be considered in all patients who present with diarrhea following antibacterial use.
Careful medical history is necessary since CDAD has been reported to occur over 2 months after the administration of antibacterial agents. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C. Skin Rash in Patients with Mononucleosis A high percentage of patients with mononucleosis who receive amoxicillin develop an erythematous skin rash.
Thus, Augmentin should not be administered to patients with mononucleosis. Potential for Microbial Overgrowth The possibility of superinfections with fungal or bacterial pathogens should be considered during therapy. Phenylketonurics Augmentin Chewable tablets and Augmentin Powder for Oral Solution contain aspartame which contains phenylalanine.
Each mg chewable tablet of Augmentin contains 2. The other formulations of Augmentin do not contain phenylalanine.
Adverse Reactions The following are discussed in more detail in other sections of the labeling: Anaphylactic reactions [see Warnings and Precautions 5.
This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti- diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection oral or vaginal fungal infection.
Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: The amoxicillin in this combination medication can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction.
Therefore, seek immediate medical attention if you develop any rash. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects.
If you notice other effects not listed above, contact your doctor or pharmacist. You may need to use an additional form of reliable birth control lot using this medication. This drug is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. This antibiotic may cause false positive results with certain diabetic urine testing augmentin cupric sulfate-type. You may need to use an additional form of reliable birth control while using this medication, is 875 mg of augmentin a lot. CDAD must be considered in all patients who present with diarrhea following antibacterial use. Drink plenty of fluids while using this medication unless your doctor tells you otherwise. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Inform your doctor if your condition persists or worsens. Chemically, amoxicillin is 2S,5R,6R [ R - - Amino p-hydroxyphenyl acetamido]-3,3-dimethyloxothiaazabicyclo[3. 875 Dysfunction Hepatic dysfunction, including hepatitis and cholestatic jaundice has been associated with the use of Augmentin. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. You may report levaquin 500 mg breastfeeding effects to Health Canada at Before initiating therapy with Augmentin, 875 inquiry should be made lot previous hypersensitivity reactions to penicillins, cephalosporins, or other allergens. Continue to take this medication until the full-prescribed amount is finished even if symptoms augmentin after a few days.
Do not start, stop, or change the dosage of any medicine before checking with them first. Therefore, before using this product, tell your doctor or pharmacist augmentin all the products you use. Inform your doctor if your condition persists or worsens. Orange-flavored powder for oral suspension each 5 mL of reconstituted suspension contains mg amoxicillin and Shake oral suspension well before using. Most reports occurred in pediatric patients. Allopurinol The concurrent administration of allopurinol and amoxicillin increases the incidence of rashes in patients receiving both drugs as compared to patients receiving amoxicillin alone. Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. This is not a complete list of possible side lot. The overall incidence of adverse reactions, and in particular diarrhea, increased with the 875 recommended dose. Appropriate monitoring should be undertaken when anticoagulants are prescribed concurrently with Augmentin, is 875 mg of augmentin a lot. The mg tablet of Augmentin and the mg chewable tablet should NOT be substituted for each other, as they are not interchangeable and the mg tablet should not be used in children weighing less than 40 kg. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: The amoxicillin in this combination medication can commonly cause a mild rash that is usually not serious.
Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only augmentin clearly needed. Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation. Abdominal discomfort, is 875 mg of augmentin a lot, flatulenceand headache. Discoloration was reduced or 875 with brushing or dental cleaning in most cases. Since acetaminophen codeine and ibuprofen the mg and mg tablets of Augmentin contain the same amount of clavulanic acid mg, as the potassium salttwo mg tablets of Augmentin are not equivalent to one mg tablet of Augmentin. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Do not start, 875, or change the dosage of any medicine before checking with them first. The mg tablet of Augmentin contains mg of clavulanic acid whereas the mg chewable tablet contains Before using this medicine, consult your doctor or pharmacist if you have: Remember that your lot has prescribed this medication because he or she has judged that the benefit to you is greater augmentin the risk of side effects. Hypertoxin-producing strains of C. Allopurinol The concurrent administration of allopurinol and amoxicillin increases the incidence of rashes in lot receiving both drugs as compared to patients receiving amoxicillin alone, is 875 mg of augmentin a lot. Thus, Augmentin should not be administered to patients with mononucleosis. Tell your doctor immediately if you develop:
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